Causal analysis approaches in Ingenuity Pathway Analysis
نویسندگان
چکیده
منابع مشابه
Causal analysis approaches in Ingenuity Pathway Analysis
MOTIVATION Prior biological knowledge greatly facilitates the meaningful interpretation of gene-expression data. Causal networks constructed from individual relationships curated from the literature are particularly suited for this task, since they create mechanistic hypotheses that explain the expression changes observed in datasets. RESULTS We present and discuss a suite of algorithms and t...
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15 صفحه اولAre causal analysis and system analysis compatible approaches?
In social science, one objection to causal analysis is that the assumption of the closure of the system makes it too narrow in scope, that is it only considers ‘closed’ and ‘hermetic’ systems thus neglecting many other external influences. On the contrary, system analysis deals with complex structures where every element is interrelated with everything else in the system. The question arises as...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt703